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On This Day   January-04  (Benjamin Rush -1746 AD)

Benjamin Rush was one of the major political leaders who participated in the American Revolution and signed the U.S. Declaration of Independence in 1776 who insisted in medical freedom as in religious freedom but was not successful making it an article of the constitution...

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Stimulus, pl. stimuli
1. A stimulant.
2. That which can elicit or evoke action (response) in a muscle,
nerve, gland or other excitable tissue, or cause an
augmenting action upon any function or metabolic process.

Origin [L. a goad]
LAW OF STIMULATION: Briefly, any stimulus that is applied to the body that is short, brief, and strong; tends to tone or stimulate. Whereas any stimulus, whether hot or cold, dry or moist, chemical or electrical; tends to sedate or depress.
This Law is based upon a time line...
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Toning, Stimulating -----------Moderation ----------------- Sedating, Depressing --------->>Analgesia
Many and far-reaching are the changes that can be induced by heat: their nature can be exemplified in the common experiences of a hot bath. When moderate heat is applied to the surface of the body, as in an ordiuary hot bath (at a temperature of roughly 105˚ F.) the skin flushes, the swcat glands are stimulated the superficial nerves are soothed; muscles and ligaments relax, respiration is quickened, and the pulse rate rises by several beats per minute. Duration of the exposure has a marked bearing upon the effects produced; it may be said that while a really bricf immersion in a hot hath has a stimulating action upon vascular, nervous and muscular tone, the effect of lingering in hot surronndings is to depress rather than to excite such tone.
The effect of cold upon the human body depends upon the degree of severity of the temperature, the time of exposure, and upon the power of the body to react to it. The body reacts more readily to a dry cold temperature than to a combination of cold with a moist atmosphere. Persons possessed of a vigorous reaction power will take no harm from extremes of cold which must prove detrimental to others lacking this special endowment. The bather who plunges into cold water becomes, if he is healthy, warmer as a result of his plunge. But no matter how healthy he may be, the time will arrive, if he stays in the cold water, when he will begin to chill. In other words, bodily reaction to cold, like bodily reaction to other circumstances, is limited in duration and in extent.
And just as their is a Law of Stimulation, there is also a Law of Adaptation, further, a Law of Addiction.
1. Preferential survival of members of a species because of a phenotype that give them an enhanced capacity to withstand the environment including the ecology.
2. An advantageous change in function or constitution of an organ or tissue to meet new conditions.
3. Adjustment of the sensitivity of the retina to light intensity.
4. A property of certain sensory receptors that modifies the response
to repeated or continued stimuli at constant intensity.
5. The fitting, condensing, or contouring of a restorative material, foil, or shell to a tooth or cast so as to be in close contact.
6. The dynamic process wherein the thoughts, feelings, behavior, and biophysiologic mechanisms of the individual continually change to adjust to a constantly changing environment. Syn: adjustment(2).
7. A homeostatic response.

Origin [L. ad-apto, pp. -atus, to adjust]
Like any other power of body or mind, the power of resisting cold is capable of cultivation. It is wise to cultivate it, since by doing so one escapes many ailments. Training of the skin to react to cold should be begun in childhood but much can be done in later if by sensible adaptation of clothing, exposure of the body to the open air, cold bathing, etc. People who should know better betray anxiety lest an open window may give them a chill they overclothe themselves with heavy garments; they refuse to sleep with wide open windows or to take sufficient exercise. And so they lose the power of resisting cold.
When cold strikes the human skin in the first instance, the skin is emptied of blood by the action of the small vessels coursing through it. The skin becomes pale. In fit, people, however the powers of resistance are mobilised almost as soon as the cold is felt. lf pallor occurs at all it lasts only a few seconds. There succeeds to it a flushing of the skin caused by an opening of the small vessels, and by a quickening of the heart's action. This is technically termed full reaction. The body is more active than it was; the blood is flowing quicker; the breathing is deeper. Cold therefore, is beneficial so long as the body can, actively respond to it. After that point has been reached it is definitely injurious and lowers the vital powers. Severe continued cold or a short exposure to very extreme cold will paralyse the local circulation and set up frost bite.
Habitual psychological and physiological dependence on a substance or practice that is beyond voluntary control.

Origin [L. ad-dico, pp. -dictus, consent, fr. ad- + dico, to say]

Addiction reinforces the phenomenon of adaption. In order for a stimulus to stimulate, adaption requires more and more of the time and intensity of the agent to have its effect.